In my particular case I create collectioned based on NetBIOS Name with wildcards, eg. MALT%A0%.
This has led to situation where a few laptops meet the criteria but I do not want them as part of the deployment collection.
Now obviously I could edit the query and add a 'NOT LIKE' myself but it would be so much easier to just right-click "Add Collection Exclusion' or something similar.
I feel like everyone could benefit from this, afterall it's just one less QoL issue.